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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

4. Precious metals: 'Going dark! Economic cycles point downward'
这造成了一种有待填补的身份认同真空。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“微博等新媒体让每个人都拥有了发言平台,如果你不能直面批评,与百姓合作,是不能做好工作的。”
Good health, good luck and much happiness throughout the year.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

上周四公布的一项数据显示,两所中国顶尖大学跻身今年《泰晤士报高等教育专刊世界大学声誉排行榜》的前20名。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

1. Hokkaido, Japan-Though known primarily to the outside world for its ski resorts and powdery snow, Hokkaido's year-round beauty might soon become a more familiar sight to foreign visitors. The new bullet-train service from Tokyo should help.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

创业者之间竞争的本质在于效率。好消息是,如今市面上已经有了好几千种优秀的应用软件,能令我们的生活变得更加轻松,但是你不可能有足够的时间把这几千种应用都试上一遍。那么,哪些应用值得你花时间试用一下呢?
这一奖项于3月14日在阿姆斯特丹公布,是基于对全球上百万名旅客的调查而选出的。
To Anita Eerland and Rolf Zwaan [THE NETHERLANDS] and Tulio Guadalupe [PERU, RUSSIA, and THE NETHERLANDS] for their study "Leaning to the Left Makes the Eiffel Tower Seem Smaller."
“这不是可持续的增长,因为它们并未被租出去,当地市场的喊价者们并不会购买。”

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

identity
The captain must steer the ship. If leadership doesn’t know where a project or company is headed, how can the company know? This isn’t just about steps or deliverables, either, but a clear vision of the department or company’s future that he or she can communicate to the employees。
在这部1998年的古装剑侠动作电影中,安东尼奥·班德拉斯扮演了一个无聊的贵族,他有时会扮成蒙面歹徒,从腐败领导人手中拯救加州的墨西哥平民。虽然佐罗听起来可能像个普通的老派超级英雄,但是《佐罗的面具》依据的故事大部分来源于现实世界中,一个叫乔伊·穆里埃塔的亡命之徒。
"It is very reassuring to learn that the government of China has set a target of 7.5 percent GDP growth while trying to keep inflation at a manageable level. It will not only maintain China's prosperity, but also help spur the regional and global economy, which Indonesia can benefit from."

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 棚改贷款审批权限未上收总行
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

v. 拥抱,包含,包围,接受,信奉

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

马自达获得了最佳轿车品牌的称号。汽车媒体一直很青睐马自达的表现,而如今的马自达汽车都在精致的内部设置和强大的驱动力上赢得了积极的反馈。上图的2016马自达第三代,在美国新闻小巧车排名中摘得桂冠,它的精准操控,强大加速度和高端室内布局,赢得了大多数汽车评论家称赞。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

哈佛大学发言人瑞秋?戴恩拒绝对该新闻发表评论。她在邮件中写道:“我们对于个别申请人的录取情况不予置评”。
许多老板都会对自己的员工负责,但是优秀的老板也会对他们自己的行为负责。这意味着他们同样会遵守为员工们设置的指导原则,并为团队的成功和失败负责任。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Annual prices had been rising as much as 9.6 per cent at the start of this year but they've cooled since then as the economy slows and many mid-sized Chinese cities suffer from a glut of apartments.
要让消费者有更多选择,从中受惠,更重要的是让我们的企业下决心,通过发扬工匠精神,使自己的产品赢得消费者的信赖。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 经济型酒店跑马圈地显疲态
Open Access Review Article

Diagnostic technologies for COVID-19: a review

《华盛顿邮报》
排在榜单第三位的是31岁的克丽茜·泰根,她在过去的12个月里赚得1350万美金,首次跻身榜单。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Ben McLannahan is US banking editor
Her predecessor David Cameron placed fifth in CNNMoney's previous ranking in March 2015 with his salary of £142,500, then worth $214,800. May is only seventh.
In 2008, China's government added an entry to the list of conditions classified as mental illnesses: "Internet addiction." According to numerous reports in state-run media, China's young people were spending too much time in Internet cafes, ignoring family or work to play online games into the wee hours, sometimes neglecting to eat, drink, or sleep, and endangering their own health.
单词receptive 联想记忆:

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 不只30城!楼市专项治理行动扩围
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

年龄:31岁

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

英国《泰晤士高等教育》专刊于上周四公布的一项调查显示,中国内地两所高校入选亚洲大学前三名。
con全部+fid相信+ent表示形容词,“…的”→自信的

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 2013陶瓷压机市场出货量增长83%
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

This is the biggest question hanging over the global economy. And the biggest risk.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

11月中国房地产价格继续下跌,因投资者把更多注意力从房地产市场转向股市。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

发布日期:2015年
But this has begun to feel less like a relevant statement about what women want now and more like a retreat; an assumption, which I would characterize as false, that the past is a safe place to dress.
Remember Anthropoid. A rather overlooked drama from earlier this year, it starred Jamie Dornan and Cillian Murphy in the story of a failed assassination attempt on Hitler's third in command, SS General Reinhard Heydrich. Another crack at this story is being attempted with HHhH, this time round with Jacks Reynor and O'Connell as the plotting soldiers, plus Rosamund Pike and Mia Wasikowska as the objects of their affections, and Jason Clarke the target of their anger.
neg否认+lect选择→不选择→忽视,不顾

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

《神奇女侠》
“My manifesto with Summly was to get our technology into as many users’ hands as possible,” Mr D’Aloisio said, pointing to Yahoo’s hundreds of millions of users. “With Yahoo’s reputation as a content portal, we have an opportunity to fundamentally change the way content is consumed.”
“…did a song and dance routine in hopes of getting the job.”
该剧在拍摄武术场景时使用的慢动作手法赢得不少好评。
切实落实脱贫攻坚责任制,实施最严格的评估考核,严肃查处假脱贫、“被脱贫”、数字脱贫,确保脱贫得到群众认可、经得起历史检验。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

2015年最需要迎头赶上的品牌:由于产品线陈旧,大众今年的销量下降了11%,影响了费迪南德o皮切的“称霸全球”计划。沃尔沃的销量则下跌了17%,自从被中国车企收购后,该公司至今还没有任何进步。
在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

荷兰合作银行认为,外汇市场波动性也可能会成为影响未来12个月大宗农产品价格的因素,法国、荷兰和德国大选可能会导致欧元贬值。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

哥伦布日在1971年成为美国假日。银行、州政府办公室、邮局和联邦机构都会放假。债券市场休市,但许多商家和股票交易所继续开放。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

[ri'dikjul?s]
The result has been increased ratings this regular season. Everything has been flipped. The offseason is thrilling, "stay on your phone every second checking what's happening" drama. The regular season is fascinating and competitive, with superstar matchups and explosive performances every night. The playoffs? Ho-hum, the Warriors win again. What's interesting is that this might be an actually better growth strategy for the league. A dynamite dynasty to attract the casual viewers who only want to see greatness, a super-compelling offseason and intriguing regular season to keep the die-hards engaged. It flips the standard models on their heads, but it also makes the best use of the NBA's ever-expanding digital presence.
[.dem?n'strein]
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 警惕首付贷换“马甲”
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The questions can seem like a sudden reversal after decades of rising multiculturalism, through the civil rights movement in the United States and the European Union’s opening up of borders.
8. The 2012 Ig Nobel Fluid Dynamics Prize
n. 浪漫的人
Brands vs the market

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

A 19-year-old girl, referred to as Guo Lingling (this may be a pseudonym), was allegedly struck and kicked repeatedly by her so-called instructors after failing to ask permission to go to the bathroom. An autopsy report showed she died from skull injuries and brain damage.
*Directing for a Variety Series: Ryan McFaul, “Inside Amy Schumer”

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

13. 《女孩帮》(Girlhood),导演:瑟琳·席安玛(Céline Sciamma)。
vi. 领先
"Metro-Goldwyn-Mayer Inc. ('MGM') today announced that the secured lenders voting in the Company's solicitation process have overwhelmingly approved its proposed plan of reorganization ('Plan'). MGM will now move expeditiously to implement that Plan, which will dramatically reduce its debt load and put the Company in a strong position to execute its business strategy. MGM is appreciative of the lenders' support."
在动画电影行业执迷于翻拍让观众有共鸣的老故事时,皮克斯却总能尝试新事物,把观众带到从未踏足的新领域。《寻梦环游记》由《玩具总动员3》导演李?昂克里奇执导,该片的视觉效果基于墨西哥的亡灵节。故事讲述了一个名叫米格尔的小男孩崇拜传奇吉他手欧内斯托?德?拉?克鲁兹,想学习如何能弹奏得和他一样好。于是他就像奥德赛一样踏上了改造性的自我发现之旅,进入死亡之地寻找那位已去世多年的偶像,还受到了一些关于创造力本质的教导。《寻梦环游记》是否能达到皮克斯2015年杰作《头脑特工队》的高度尚未可知,但这部电影绝对是一场视觉盛宴。该片将于11月15日在法国上映,11月22日在美国、克罗地亚和菲律宾上映,11月30日在以色列上映。(资料来源:迪士尼/皮克斯)
Lawyers are inherently cautious but most have realised that technology is crucial to crunching through the vast amount of information they handle. Without it, certain document heavy processes, such as disclosure and compliance, would be nearly impossible.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Piggyback riders are designed especially for small children and toddlers, to lessen the parents’ struggles.
“One person said he was going to the men’s room and didn’t return.”
6.You Spend Time Looking For Other Jobs

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

7)让我来唱黑脸:想找一种婉转的批评方式?将对话转变为一场操练,你在其中扮演被孤立的一方,执行一项职能:戳穿(对方言语中的)逻辑漏洞及其攻击计划中的漏洞。你使用此条策略,一定要强调一点,千万不要在这些观点中掺杂个人情绪。
"He said if he didn't get that package within the next 53 years, he would call to complain," university spokeswoman Christine Kindl told Reuters news agency.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 巨头扎堆进入银川楼市量价齐升
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

A candidate's age is no gauge of their effectiveness, Sonneborn tells PEOPLE, saying that despite Donald Trump being the oldest person elected to the U.S. Presidency, “He tweets like a kindergartener.”
il不+legal合法的→不合法的
创造一个学习空间

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 彻底打破楼市路径依赖
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

The report shows Cases of dishonesty connected to e-commerce platforms and enterprises, logistics companies, third-party payment platforms and consumers in a five-day period from Nov 11 to 15 increased 57.49% compared to last year.
今年选秀中还有很多选秀权交换的情况,有湖人给费城的前三保护的选秀权,有孟菲斯给丹佛的前五保护的选秀权,还有那个无耻的萨克拉门托给芝加哥的前十保护的选秀权(然而费城球队会控局的,他们的前总经理山姆-辛基会来复仇的)。
While a way must be found to aggregate those views, it will always be defective.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 整装卫浴行业将迎来爆发式增长
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

华为的品牌价值增长22%,至190亿美元,其排名上升20个位次,至第50位。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

退出单向乐队之后,哈里·斯泰尔斯可以去自己想去的任何地方。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

According to a research report on 2016 graduates released by 51job.com, a leading job hunting platform in China, 52.11% of college graduates found employment or started their own business.
The US and UK’s losses will be Germany, Sweden and Canada’s gain, as founders set up in the cosmopolitan hubs of Berlin, Stockholm and To

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

雅虎宣布数据外泄影响数百万人引人震惊,勒索软件WannaCry和BadRabbit的网络攻击引人担忧,2017年我们经历了数起严重的网络安全灾难。
立场:支持移民改革
Most of the cellphones sold in 2016 are smart phones installed with the Android system and 4G ready, according to the report.
1.你一夜之间成了领英平台的香饽饽。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

衷心祝福来年快乐、幸运!
So, yeah, I think they should tank and they might even be able to get some good value for Ibaka in a trade even if it would be a really quick about-face. God they're weird.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

近几年,得益于世界日新月异,就像保护异性夫妻一样, LGBT群体(女同性恋、男同性恋、双性恋、跨性别人士)也会得到同样的权利保障。事实上,如今60%的美国人承认同性婚姻的合法性,如果你问那剩余的40%呢?我们可以告诉你美国的其他地方以及世界的其他地方,例如俄罗斯,很快都会赶上脚步。
至少在城市大部分人能去上班是不可能的,这将影响多个行业,包括金融、广告、医疗保健和艺术。近两天城市的交通线路、桥梁、隧道都瘫痪了,在最新的报告中,地铁到下周可能会正常运作。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

近日,英国《金融时报》披露了中国北方很多地区例行公布的关于国内生产总值(GDP)的虚假数据。在那些地区,可靠的替代证据表明,地方政府“抹平”了经济增长数字。他们人为地推高了2012年至2016年期间的增长数字,掩盖了真实的低迷期,去年又掩盖了真正的复苏。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

恭贺新年。
['delikit]
卡梅隆·安东尼
PPI已连续下降44个月,反映出建房材料和原料的供应过剩,以及重工业的产能过剩。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

特斯拉的积压订单达到2.26亿美元。到2014年之前,特斯拉的生产速度大约为每周1000台,也就是说这些订单需要30周才能消化完。
[k?ut?]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

至少希拉里今年赢得了点什么。我相信她会非常兴奋。
在2010年世界杯中,智利当属最振奋人心的一支队伍,并在最近的温布利比赛中让英格兰队在赛场上四处兜转,不过,如果哥伦比亚队能够融合射手拉达梅尔·法尔考(Radamel Falcao),那么这支队可能会让一两支队伍神伤了。因此,在所有的南美洲球队中,似乎只有厄瓜多尔难以走出小组赛,而其余的所有国家都有能力奋战到后面的阶段。
获奖者:侯任总统唐纳德?特朗普和希拉里·克林顿(共同获奖)

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 混凝土行业表彰绿色生产示范企业
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Immigrant populations in Arkansas, North Carolina and Tennessee have more than tripled since 1990, noted Lee Drutman, a senior fellow at the New America Foundation, in an analysis for Vox. Anxiety over those changes may explain why the Republican Party became so much more focused on limiting immigration over that period — and why white voters in those states overwhelmingly support Mr. Trump.
OUTDOOR SPACE: Steps down from the patio is a walled garden with a lawn and a fountain. The property is 0.10 acre.
肯尼迪中心为她的善举给她颁发了希望的波澜奖(the Ripple of Hope Award),泰勒也成为此奖项的最年轻获得者。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

In 2002, Marc Cherry (the creator of Desperate Housewives) was watching the news with his mother in her home. The lead story on the news that day (and many days before) was the Andrea Yates trial. Andrea was on trial for drowning her five children in the bathtub. Marc turned to his mother and asked, "Could you imagine a woman being so desperate that she would murder her own children?"
在那之前,她曾出演过大受欢迎的情景剧,并且也因饰演的角色而小有名气。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 物流地产受追捧
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Finance and real estate made up the backbone of home-grown brands, with 38 and 23 companies coming into the list respectively, and accounting for 30 percent of the brands on the list.
Overall twenty-eight thousand bombs and other munitions were exploded over Yugoslavia a country the size of Ohio. William Cohen then secretary of defense characterized Allied Force as “the most precise application of airpower in history.” Some five hundred civilians died in the bombing a remarkably low number for such a high number of munitions expended. In its own account of the campaignNATO stresses that targets were “carefully sexted” and that “massive effort was made to minimise the impact of the air campaign on the Serb civilian population.”
Remedy: Make a budget. If you don’t know how much money you need to live the lifestyle you feel comfortable with, you can’t accurately project whether switching jobs for a $10K pay bump is actually a good deal. Making a pros and cons list when comparing your current job with a new opportunity is also helpful. If the only advantage a job offers is a bigger pay check, you can weigh that against longer hours, a more onerous commute and increased reporting responsibilities. Keep in mind that research shows that increases in happiness based on earnings peak at about $75K. Incomes above this level don’t increase your feeling of well-being on a day-to-day basis. So, if you think a jump up to $85 or $90K will make you feel less morose when your alarm goes off, you might want to look at addressing some of the non-monetary factors in your life that are contributing to your dissatisfaction.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

中国科学技术协会书记处书记王春法对撤稿事件表示深切关注,事件发生几天前,他刚在北京与施普林格自然集团大中华地区总裁安诺杰会面沟通。
Apple will this week test its customers’ loyalty, buying power and enthusiasm for innovation when it unveils the first iPhone to cost as much as $1,000.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Here are the 10 winners of the 2012 Ig Nobel Prizes given to scientists, writers, and peacemakers who make silly but thoughtful contributions to the world, or as the Annals of Improbable Research puts it, "first make people laugh, and then make them think." I can vouch for them making us laugh!
WHAT: A house with three bedrooms, two full bathrooms and two half-bathrooms
3.人工胰腺

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

vi

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

回归白人占统治地位的社会,实施排外的国民身份认同,这样的事情不太可能发生。移民一旦停止,肯定会损害西方国家的经济;如果大举驱逐已经到达的移民,肯定会引起社会与道德上的损失。那些看似来“插队”的人群其实是在寻觅一个机会,加入到一个长久以来把他们拒之门外的进程中来。
人力资源机构罗伯特?哈夫国际公司(Robert Half International)最近针对4,000名企业高管进行了一项调研。其中有88%的人预计,未来一年,公司的业务将有所好转。这不失为最鼓舞人心的消息了。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Best wishes for the holidays and happiness throughout the New Year.
intelligence

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

年龄:44岁
2011年诺贝尔和平奖被授予利比利亚总统埃伦.约翰逊.瑟利夫,利比利亚和平活动人士蕾曼.格鲍伊和也门妇女权利倡导者塔瓦库尔.卡门。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

China's online game revenue in 2008 was CNY20.8 billion, accounting for about 27% global share, ahead of South Korea at 21% and slightly behind the U.S. at 29%, according to an earlier report by Shanghai-based market research firm iResearch. The firm also predicted that China is likely to surpass the U.S. to become the world's largest by the end of 2009.
4. Booing isn't just for pantomimes

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

单词calendar 联想记忆:

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

创始人的心态将为公司定下基调。消极、懒惰和理所应当的心态,不仅浪费时间和金钱,还会损害你的信誉。成功很大程度上取决于能否在犯错后从容地接受批评。直面挑战可以让一位普通的公司老板变成真正的领导者。
“如果我们能找到在两个地方都购物的人,那就非常有价值。你知道他们是谁,他们买什么,他们哪些方面花钱,”哈勃补充说。“你可以给他们更加个人化的体验。”
信任感依然会是商业领域中唯一且最关键的问题。
劳伦斯2016年的收入比2015年(5200万美元)减少了11.5%。本周四福布斯杂志还将发布2016年收入最高的男星排行榜。去年荣膺榜首的是小罗伯特-唐尼,收入约为8000万美元。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Some 150,000 rural residents in southwest China's Tibet Autonomous Region escaped poverty last year, according to the Tibet Poverty Alleviation Office.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

此外,他指出,鉴于中国正在努力推动本国经济从出口转向消费的再平衡(从而减少对中间投入品的进口需求),再加上“中国政府鼓励使用国内供应商的政策”和其他地区保护主义的兴起,“全球贸易在短期内不太可能回暖”。
manifesto
In a statement given to the website Kotaku, Epic Games said the lawsuit was a result of Mr Rogers "filing a DMCA counterclaim to a takedown notice on a YouTube video that exposed and promoted Fortnite Battle Royale cheats and exploits."

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 2015年中国石材十大品牌企业排名
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

一位来自美国佛罗里达州的少女引起了世人的惊叹,因为她长得酷肖迪士尼动画电影《冰雪奇缘》中的艾丽莎女王。
公司:技术服务公司Binary Group

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: LED照明转型不易 三大挑战须重视
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

n. 舒适,安逸,安慰,慰藉
[k?mpi'tin]

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

In a sign that civil service jobs may be losing their appeal, a report issued by recruitment website Zhaopin in late March said more than 10,000 public sector employees, including civil servants and staff members at public institutions, had submitted their resumes to potential employers through the site in just two months. The number was 34 percent higher during the same period last year, the report said.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

'I have to echo that, You have steel in your eyes when you sing. You are totally focused. The first time I heard this song it was fantastic, well this was a step up,’ Simon shared.
5. Sunset
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

“有个女员工打包好自己的东西就一言不发地走了。”
The number of students who will study abroad after graduation has also seen a drop, down from 4.8 percent last year to 3.4 percent.
Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
指数:96.6

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

While Insead’s joint programme dropped back into second place, its single-school programme moved up three places to fourth, a place it last occupied in 2011.
实际上,有一句俗语就是这样说的:“如果你拥有了龟兹,那么西域99%的城邦都会服从你。”

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

去年八月北韩一位边界士兵试图射击一些气球,但最终引致了边界双方的一场重机枪交火。
The Asia-Pacific is the common home of all countries in the region. China does not want to see any party in the Asia-Pacific region feel compelled to choose sides under the influence of a Cold-War mentality.
What deserves to be mentioned the most is, Uber and Tesla Motors Inc did not make it to the list. "Both Uber and Tesla do innovate, but not at a sufficient level to feature in the Top 100 list of innovative organizations around the globe as measured by patent metrics of volume, success, globalization and impact. They neither have sufficiently large portfolios to qualify for inclusion with less than 100 granted inventions during 2010-2014," Stembridge said.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

The government's next snapshot of the job market, due Friday, will be distorted by Sandy, which devastated the Northeast in late October, leaving many jobless. Economists say Sandy could temporarily knock anywhere from 100,000 to 150,000 off of the government's jobs tally for November, resulting in job growth of under 100,000 or even much less.[qh]
Singapore tops the list as the most expensive city for the third time in a row, but in a year when costs around the world have been highly volatile.

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